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All You Need to Know about Cat & Dog Lymphoma

Welcome to another compassionate exploration at The Gentle Vet, where our hearts are always open to the needs of our furry families. Today, we delve into an essential topic for pet owners: understanding lymphoma in cats and dogs. This condition, while serious, can often be managed with care, love, and the right medical intervention. Our aim is to guide you through recognising the signs, understanding the diagnosis process, and exploring the treatment options available for your cherished companion.

Understanding Lymphoma in Pets

Lymphoma, a type of cancer that affects the lymphocytes (a vital component of the immune system), is among the most common cancers diagnosed in cats and dogs. It can manifest in various forms, affecting different parts of the body, leading to a range of health challenges.

Common Types of Lymphoma in Pets

The condition can be broadly categorised into several common types:


  • Intestinal Lymphoma in Cats: This type targets the gastrointestinal tract, leading to symptoms like vomiting, diarrhoea, weight loss, and not eating. It’s one of the most common forms of lymphoma in cats, requiring prompt diagnosis and treatment to manage its effects.
  • Mediastinal Lymphoma in Cats: Affecting the organs in the chest, such as the lymph nodes, thymus, or mediastinum, this lymphoma can cause breathing difficulties, lethargy, and increased thirst or urination. It may be identified through chest X-rays or ultrasound.
  • Multicentric (Systematic) Lymphoma in Dogs: The most prevalent form of lymphoma in dogs, multicentric lymphoma, affects the lymph nodes around the body. Owners might notice swelling in nodes under the neck, behind the knees, or elsewhere. Symptoms also include lethargy and weight loss.
  • Alimentary Lymphoma in Dogs: This type specifically impacts the gastrointestinal tract, similar to its feline counterpart, leading to symptoms such as vomiting, diarrhoea, and significant weight loss. Early detection through diagnostic imaging and biopsies is crucial for effective management.
  • Mediastinal Lymphoma in Dogs: Like in cats, this affects the mediastinal and thoracic lymph nodes in dogs, causing symptoms such as difficulty breathing, swelling of the face or front limbs, and increased thirst and urination. Diagnostic tests include thoracic imaging.
  • Extranodal Lymphoma in Dogs: This form occurs when lymphoma develops outside of the lymph nodes, potentially affecting the kidneys, liver, eyes, or skin. Symptoms vary widely depending on the organs involved but can include lethargy, unusual lumps or swellings, and changes in organ function.

Diagnosis and Treatment Options

Diagnosing lymphoma in cats and dogs involves a comprehensive approach to ensure accurate identification and staging of the disease, crucial for determining the most effective treatment plan. At The Gentle Vet, our dedicated team of pet cancer vets uses a combination of advanced diagnostic tools and techniques to provide a definitive diagnosis and tailor treatment to each pet’s specific needs.

The diagnosis process typically starts with a physical examination, during which a veterinarian will look for enlarged lymph nodes or other signs indicative of lymphoma. This initial assessment is often followed by:


  • Biopsies and Cytology: Taking a sample of tissue or cells from affected areas or lymph nodes to examine under a microscope for the presence of cancerous cells.
  • Blood Tests: These can reveal abnormalities in white blood cell counts or other indicators of lymphoma.
  • Imaging Tests: X-rays, ultrasounds, and CT scans are used to identify the location and extent of lymphoma within the body.
  • Bone Marrow Aspiration: In some cases, examining the bone marrow is necessary to determine if the cancer has spread.

Treatment for lymphoma then varies based on the type and stage of cancer, as well as the overall health of the cat or dog. Options include:


  • Chemotherapy: The most common treatment for lymphoma, involving drugs that target and kill cancer cells. Treatment protocols vary, but our goal is to maintain your pet’s quality of life with minimal side effects.
  • Radiation Therapy (Not available in Singapore): Used for localised lymphoma, radiation targets specific areas to shrink tumours and alleviate symptoms, often in conjunction with chemotherapy.
  • Immunotherapy: A newer form of treatment that helps the immune system recognise and fight cancer cells more effectively. This option is gaining traction as part of a comprehensive approach to cancer care.
  • Surgery: In cases where lymphoma is localised and accessible, surgery may be performed to remove tumours. This is less common but can be effective for certain types of lymphoma.
  • Supportive Care: Managing symptoms and maintaining quality of life are paramount. This includes pain management, nutritional support, and, when necessary, hospice care for pets in the advanced stages of lymphoma.

How to Care for Cats & Dogs with Lymphoma

Managing a pet’s chronic condition requires a delicate balance of medical treatment and home care to ensure they remain comfortable.

Medical Treatment Tips

As a pet owner, your role in your cat’s or dog’s medical treatment is crucial. Here are ways you can support their lymphoma treatment journey:


  • Stay Informed: Understand the specifics of your pet’s lymphoma type and the expected outcomes of their treatment plan. Knowledge empowers you to make informed decisions.
  • Medication Management: Keep a strict schedule for any prescribed medications. Use reminders or charts to stay organised and ensure doses are not missed.
  • Monitor Side Effects: Be vigilant about potential side effects of chemotherapy or other treatments, such as lethargy, nausea, or changes in appetite. Report these to your vet promptly.
  • Hydration is Key: Ensure your pet stays well-hydrated, especially if they are experiencing vomiting or diarrhoea due to treatment.
  • Regular Check-Ups: Maintain a regular schedule of vet visits to monitor the progress of the treatment and adjust as necessary.
  • Comfort During Vet Visits: Bring their favourite blanket or toy to vet visits to help ease anxiety.

Home Care Tips

At The Gentle Vet, our compassionate approach to cancer treatment for cats and dogs is rooted in the understanding of the emotional and physical challenges faced by pets and their families during such a difficult time. 


As the leading 24-hour pet clinic in Singapore, we are dedicated to providing the most advanced and empathetic care for pets diagnosed with lymphoma. Our team, including experienced geriatric veterinarians and oncologists, crafts individualised treatment plans that may include oncological surgery, radiation therapy, chemotherapy, and immunotherapy, all aimed at targeting cancer cells while prioritising the comfort and safety of your pet. 


We stand with pet owners every step of the way. Get in touch with us to find out more.

Cat & Dog Lymphoma Treatment and Care at The Gentle Vet

For comprehensive geriatric veterinary care, consider The Gentle Vet. Our team is experienced in handling the unique challenges faced by senior pets. We provide tailored care plans, including pain management strategies and palliative care options, ensuring your pet’s golden years are as comfortable as possible.
As you navigate the year ahead with your older pet, remember that their needs may change, but your love and care should remain constant. Embrace these changes and continue to provide the nurturing environment they deserve. For any specific advice on geriatric dog or cat care, feel free to contact us. Our team is dedicated to supporting you and your ageing companion every step of the way.

Get Help from The Gentle Vet

Chronic conditions in pets, such as dog epilepsy, cat kidney disease, or allergies in your furry companion, require attentive, ongoing care. By understanding these conditions, adhering to prescribed treatments, making dietary adjustments, and maintaining open communication with your veterinarian, you can significantly enhance your pet’s comfort and quality of life.
Remember, at The Gentle Vet, we’re here to support you every step of the way in your pet’s journey through their golden years. For specific concerns — like cat arthritis treatment, dog arthritis treatment, or for a pet cancer vet  — don’t hesitate to reach out to us. We are committed to providing compassionate, comprehensive care for your beloved companion, through it all.
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